Succinimidyl iodoacetate (SIA) is a heterobifunctional protein crosslinker with a short spacer arm (1.5 Å). SIA is reactive towards amino groups and sulfhydryl groups. SIA is a protein crosslinker commonly used to couple lysines on one protein and cysteine residues on another protein or antibody.

Package Sizes: 100 mg and 1 gram

Product Numbers: 13408-100 and 13408-1

Product Name: SIA Crosslinker

Alternative Names: SIA; Succinimidyl iodoacetate; NHS Iodoacetate; SIA NHS; 39028-27-8; C6H6NO4I; Iodoacetic acid NHS ester; amino sulfhydryl reactive crosslinker; thiol reactive crosslinker; C6H6INO


Appearance: White to Off-White Solid

Purity: is ≥ 95% by quantitative NMR

Storage: 4 °C, protected from moisture

Properties Physical State: Solid

CAS#: 39028-27-8

Chemical Formula: C6H6INO

Molecular Weight: 237.00

Spacer length: 1.5 Å

Melting Point: 148 °C (Lit)

Country of Origin: USA

Tariff Code: 2925.19.9100